Research Labs

Our innovative research focuses on four areas:

  1. Basic research
  2. Next-generation therapeutics
  3. HIV prevention-vaccine development
  4. Passive administration of neutralizing antibodies and microbicides
  • The Goff lab studies the life cycle of retroviruses, and performs screens to identify and characterize restriction factors that inhibit virus replication and the host factors that they require.

  • The Guo Lab uses bioinformatics to study immune responses to pandemic and disease-related viruses, focusing on countermeasures for pandemic preparedness and antibody therapies for various diseases.

  • The Ho Lab is committed to finding scientific solutions to end the HIV/AIDS pandemic and using the techniques acquired in their decades of HIV research to the novel coronavirus SARS-CoV-2.

    David Ho and Yaoxing Huang
  • The Huang Lab devotes efforts to develop HIV vaccine and antibody-based strategies and long-acting antiretroviral drugs as pre-exposure prophylaxis to halt or slow the spread of AIDS.

  • The Iketani Lab is focused on developing scalable strategies that contribute to answering basic and translational virology questions, particularly for pandemic preparedness and virological discovery.

  • The Kwong-Shapiro Lab focuses on structural vaccinology to advance antibody therapeutics and vaccines. Their research has contributed to the design of vaccines against HIV-1, influenza A, and RSV.

    Jordan Becker, Nicholas Morano, Peter Kwong, Ryan Roark, Lawrence Shapiro in an office
  • The Meyers lab addresses health inequity by accelerating translation of scientific discoveries into public health interventions accessible to marginalized populations, with a particular focus on HIV.

  • The focus of the Sabo Lab is to expand our understanding of cellular host factors and their interaction with specific infecting viral pathogens: HIV-1 and the human respiratory syncytial virus (HRSV).

    Microscopic imagery of a cell
  • The goal of the Sheng Lab is to use interdisciplinary approaches to understand the mechanisms of antibody maturation and disease etiology, and to find therapeutic targets for disease prevention.

  • The Tsuji Lab's research projects are applied and translational, seeking to further understanding of host immune system for development of effective vaccines against infectious diseases and cancer.

  • The focus of the Wu Lab is to elucidate the mechanisms by which the HIV-1 envelope glycoprotein elicits neutralizing antibody responses in humans and rhesus macaques for HIV-1 vaccine development.

  • The Yamashita Lab studies the biology of human immunodeficiency virus to elucidate the fundamental principles of viral replication and to develop novel drug design strategies.